syndesi therapeutics products

Mar 1, 2022. | Syndesi Therapeutics is developing molecules that uniquely modulate the synaptic vesicle protein SV2A, which plays a central role in synaptic transmission (the communication between neurons in the brain). Syndesi Therapeutics develops a drug candidate for the treatment of consecutive cognitive disorders of various neurological conditions. Syndesi Therapeutics is a clinical stage biotechnology company pioneering the development of novel therapeutics that modulate synaptic function to relieve the symptoms of cognitive impairment. Under the terms of the agreement, AbbVie will pay Syndesi shareholders a $130 million upfront payment with the potential for Syndesi shareholders to receive additional contingent payments of up to $870 million based on the achievement of certain predetermined milestones. COPENHAGEN, Denmark, March 1, 2022 /PRNewswire/ -- Novo Holdings, a leading international life sciences investor, today announces that its portfolio company Syndesi Therapeutics ('Syndesi'). AbbVie's mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. Before engaging, please read and adhere to our established community guidelines for each channel. Developer of drug molecules designed to treat cognitive impairment. Syndesi Therapeutics's key executives include Jonathan Savidge and 6 others. In-Line Products . Novo Holdings and Fountain Healthcare Partners are the most recent investors. Country: Belgium. Jonathan Savidge, Chief Executive Officer, Syndesi Therapeutics, said: "We have been impressed with the vision of AbbVie's neuroscience R&D team, who share our view on the therapeutic potential of SDI-118 in a range of neurologic diseases. Syndesi was created through a partnership between UCB Biopharma SRL and a syndicate of Belgian and international investors to further develop novel SV2A modulators that had been originally discovered by UCB. These press releases remain on AbbVie's website for historical purposes only. AbbVie undertakes no obligation to release publicly any revisions to forward-looking statements as a result of subsequent events or developments, except as required by law. To connect with Syndesi Therapeutics employee register on SignalHire. AbbVie has acquired Belgium-based company Syndesi Therapeutics in a deal worth up to $1bn, expanding its neuroscience portfolio.. AbbVie has bolstered its neuropsychiatric and neurodegenerative portfolio with the acquisition of Belgium-based Syndesi Therapeutics in a deal valued at up to $1 billion. The company has also benefited from support from the Walloon Region. Additional information about the economic, competitive, governmental, technological and other factors that may affect AbbVie's operations is set forth in Item 1A, "Risk Factors," of AbbVie's 2021 Annual Report on Form 10-K, which has been filed with the Securities and Exchange Commission, as updated by its subsequent Quarterly Reports on Form 10-Q. On Mar 2, 2022. Launching Soon Launching Soon Launching Soon Launching Soon . "With AbbVie's acquisition of Syndesi, we aim to advance the research of a novel, first-in-class asset for the potential treatment of cognitive impairment associated with neuropsychiatric and neurodegenerative disorders.". WhatsApp acquired by Facebook). Syndesi's unique molecules act pre-synaptically to enhance synaptic efficiency by positively modulating the function of synaptic vesicle protein 2A (SV2A), which plays a central role in regulating neurotransmission. | SV2A plays a central role in synaptic transmission (connections between neurons). Sign up YOU ARE ABOUT TO LEAVE FOR A 3RD PARTY WEBSITE. 310.739.9937. Jonathan Savidge Chief Executive Officer John Kemp Chief Scientific Officer Torsten Madsen Chief Medical Officer Maeve Duffy Head of Clinical Operations Steven Ramael Medical Director Jean Combalbert The information in the press releases on these pages was factually accurate on the date of publication. Syndesi Therapeutics is developing molecules that uniquely modulate the synaptic vesicle protein SV2A, which plays a central role in synaptic transmission (the communication between neurons in the brain). Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia, r adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. AbbVie Acquires Syndesi Therapeutics, Strengthening Neuroscience Portfolio. The mechanism is currently being evaluated . Syndesi Therapeutics General Information. The words "believe," "expect," "anticipate," "project" and similar expressions, among others, generally identify forward-looking statements. Launching Soon Launching Soon Launching Soon Launching Soon . Btiment Le Parc Cookie Settings. UCB identified novel modulators of SV2A that show pro-cognitive properties in preclinical models. With an upfront payment of $130 million, AbbVie gains Syndesi's portfolio of novel modulators of the synaptic vesicle protein 2A (SV2A), including its lead molecule SDI-118. Personalize which data points you want to see and create visualizations instantly. Syndesi Therapeutics is building upon a rich legacy of research on SV2A conducted at UCB. AbbVie assumes no duty to update the information to reflect subsequent developments. The company's drugs can modulate the synaptic vesicle protein to handle the transmission between neurons in the brain to effectively treat Alzheimer's and other disorders with cognitive impairment, enabling healthcare providers to treat these diseases with the right . Founded in December 2017 and based in Belgium, Syndesi is a clinical stage biotechnology company pioneering the development of novel therapeutics that modulate synaptic function to relieve the symptoms of cognitive impairment. Westside Therapeutics Westside Therapeutics Westside Therapeutics. A regenerative therapy company - Bone Therapeutics. "There is a major unmet need for new therapies that can help improve cognitive function in patients suffering from difficult-to-treat neurologic diseases," saidTom Hudson, M.D., senior vice president, R&D, chief scientific officer, AbbVie. With the support of our investors and other stakeholders, Syndesi's goal is to demonstrate the potential of these molecules to reduce the symptoms of cognitive impairment in patients with Alzheimer's Disease and related conditions. Regulating synaptic transmission represents a promising approach to treating Alzheimer's Disease and other disorders with cognitive impairment. Synaptic dysfunction is believed to underlie the cognitive impairment seen in multiple neuropsychiatric and neurodegenerative disorders. Company Type For Profit. Syndesi Therapeutics uses 8 technology products and services including HTML5, Google Analytics, and Microsoft Outlook, according to G2 Stack. Their latest funding was raised on Sep 28, 2020 from a Series A round. Find company research, competitor information, contact details & financial data for Syndesi Therapeutics of Ottignies-Louvain-la-Neuve, WALLOON BRABANT. Revenues for in-line products in the third quarter were $8.1 billion compared to $7.7 billion in the prior year period, representing an increase . Syndesi Therapeutics serves customers worldwide. Company. AbbVie announced it has completed the acquisition of Syndesi Therapeutics SA, which will help to expand AbbVie's neuroscience portfolio. Readers should not rely upon the information in these pages as current or accurate after their publication dates. They are also entitled to get further contingent payments of up to $870m on meeting specific pre-set milestones. The mechanism is currently being evaluated for the potential treatment of cognitive impairment and other symptoms associated with a range of neuropsychiatric and neurodegenerative disorders, such as Alzheimer's disease and major depressive disorder. "I am delighted with the closing of this deal. Syndesi Therapeutics. from 8 AM - 9 PM ET. SaaS, Android, Cloud Computing, Medical Device), Where the organization is headquartered (e.g. Regulating synaptic transmission represents a promising approach to treating Alzheimer's Disease and other disorders with cognitive impairment. Syndesi has an exclusive license to its . OM DAOM L.Ac. "I am delighted with the closing of this deal. Syndesi's unique molecules act pre-synaptically to enhance synaptic efficiency by positively modulating the function of synaptic vesicle protein 2A (SV2A), which plays a central role in regulating neurotransmission. 2022 PitchBook. To improve patient outcomes by developing and delivering molecular diagnostics and therapeutics (theranostics). UCB spins out neuro startup with 17M from Novo, Johnson & Johnson Syndesi Therapeutics. Some statements in this news release are, or may be considered, forward-looking statements for purposes of the Private Securities Litigation Reform Act of 1995. For further information Under the terms of the agreement, AbbVie will pay Syndesi shareholders a $130 million upfront payment with the potential for Syndesi shareholders to receive additional contingent payments of up to $870 million based on the achievement of certain predetermined milestones. Syndesi has an exclusive license to its platform technology from UCB, the leading company in SV2A research. According to the deal, shareholders of Syndesi will receive an upfront payment of $130m from AbbVie. With an upfront payment of $130 million, AbbVie gains Syndesi's portfolio of novel modulators of the synaptic vesicle protein 2A (SV2A), including its lead molecule SDI-118. Main article: Alzheimer's disease Syndesi Therapeutics is developing drugs to treat consistent cognitive disorders in various neurological conditions.. History 2022: AbbVie bought Syndesi Therapeutics for $1 billion. AbbVie will pay Syndesi's shareholders a $130 million upfront payment with the potential for Syndesi's shareholders to receive additional contingent payments of up to $870 million based on the achievement of certain predetermined milestones. Now, as part of AbbVie, the program is well positioned to move into later stages of clinical development.". Subscribe for email alerts 01 Mar 2022. Founded in December 2017 and based in Belgium, Syndesi is a clinical stage biotechnology company pioneering the development of novel therapeutics that modulate synaptic function to relieve the symptoms of cognitive impairment. Cleary Gottlieb Steen & Hamilton LLP acted as legal counsel to AbbVie. Jonathan Savidge, Chief Executive Officer, Syndesi Therapeutics, said: "We have been impressed with the vision of AbbVie's neuroscience R&D team, who share our view on the therapeutic potential of . Ut enim ad min, To view Syndesi Therapeuticss complete valuation and funding history, request access, To view Syndesi Therapeuticss complete cap table history, request access, Youre viewing 5 of 50 competitors. AbbVie is providing these links to you only as a convenience and the inclusion of any link does not imply endorsement of the linked site by AbbVie. This acquisition gives AbbVie access to Syndesi's portfolio of novel modulators of the synaptic vesicle protein 2A (SV2A), including its lead molecule SDI-118. Syndesi Therapeutics offers modulators to improve cognition in diseases such as alzheimer's disease and other conditions causing cognitive impairment. Get the latest business insights from Dun & Bradstreet. UCB identified novel modulators of SV2A that show pro-cognitive properties in preclinical models. Bone Therapeutics is an advanced biotechnology company with a unique approach to the development of cell therapy products for orthopaedics and bone diseases. It has been a pleasure to partner with our investors to investigate the potential of SDI-118 in early clinical studies. Active, Closed, Last funding round type (e.g. Such risks and uncertainties include, but are not limited to, failure to realize the expected benefits from AbbVie's acquisition of Allergan plc ("Allergan"), failure to promptly and effectively integrate Allergan's businesses, competition from other products, challenges to intellectual property, difficulties inherent in the research and development process, adverse litigation or government action, changes to laws and regulations applicable to our industry and the impact of public health outbreaks, epidemics or pandemics, such as COVID-19. This acquisition gives AbbVie access to Syndesi's portfolio of novel modulators of the synaptic vesicle protein 2A (SV2A), including its lead molecule SDI-118. On March 1, 2022, the American pharmaceutical giant AbbVie completed the acquisition of the Belgian biotechnology Syndesi Therapeutics. This acquisition gives AbbVie access to Syndesi's portfolio of novel modulators of the synaptic vesicle protein 2A (SV2A), including its lead molecule SDI-118. Synaptic dysfunction, with the consequent disruption of connectivity bet ween brain regions, underlies cognitive impairment seen in multiple CNS . AbbVie undertakes no obligation to release publicly any revisions to forward-looking statements as a result of subsequent events or developments, except as required by law. UCB identified novel modulators of SV2A that show pro-cognitive properties in preclinical models. Syndesi's Series A financing was co-led by Novo Holdings together with Fountain Healthcare Partners, with participation from Johnson & Johnson Innovation JJDC, Inc., SRIW (Socit Rgionale d'Investissement de Wallonie), V-Bio Ventures and Vives Fund, along with UCB Ventures. The North Chicago-based pharmaceutical giant (NYSE: ABBV . - Expands AbbVie's neuroscience portfolio, adding first-in-class modulators of the synaptic vesicle protein 2A, including lead molecule SDI-118 currently in Phase 1b studies. Privacy policy Synaptic dysfunction is believed to underlie the cognitive impairment seen in multiple neuropsychiatric and neurodegenerative disorders. "There is a major unmet need for new therapies that can help improve cognitive function in patients suffering from difficult-to-treat neurologic diseases," saidTom Hudson, M.D., senior vice president, R&D, chief scientific officer, AbbVie. Win whats next. Regulating synaptic transmission represents a promising approach to treating Alzheimers Disease and other disorders with cognitive impairment. The lead molecule, SDI-118, is a small molecule currently in Phase 1b studies, which is being evaluated to target nerve terminals to enhance synaptic efficiency. Unless otherwise specified, all product names appearing in this Internet site are trademarks owned by or licensed to AbbVie Inc., its subsidiaries or affiliates. - Expands AbbVie's neuroscience portfolio, adding first-in-class modulators of the synaptic vesicle protein 2A, including lead molecule SDI-118 currently in Phase 1b studies, - Novel mechanism will be evaluated for the potential to mitigate synaptic dysfunction associated with cognitive deficits across a range of neuropsychiatric and neurodegenerative disorders. The UK Life Sciences team advised Syndesi Therapeutics and its shareholders on Syndesi's acquisition by AbbVie (NYSE: ABBV). AbbVie (NYSE: ABBV) today announced it has completed the acquisition of Syndesi Therapeutics SA, which will help to expand AbbVie's neuroscience portfolio. Copyright 2022 AbbVie Inc. North Chicago, Illinois, U.S.A. The lead molecule, SDI-118, was discovered by UCB before being out-licensed to Syndesi as of 2018. Phone Number +32 10 280 238. "We have been impressed with the vision of AbbVie's neuroscience R&D team, who share our view on the therapeutic potential of SDI-118 in a range of neurologic diseases," said Jonathan Savidge, chief executive officer, Syndesi Therapeutics. Funding Rounds Number of Funding Rounds 3 Total Funding Amount 26.2M The lead molecule, SDI-118, was discovered by UCB before being out-licensed to Syndesi as of 2018. PitchBooks comparison feature gives you a side-by-side look at key metrics for similar companies. It has been a pleasure to partner with our investors to investigate the potential of SDI-118 in early clinical studies. AbbVie Inc. on Tuesday said it acquired Belgian clinical-stage biotechnology company Syndesi Therapeutics SA for up to $1 billion in a deal that expands its neuroscience portfolio. Belgium, the general policy of protection of personal data. Syndesi Therapeutics is developing molecules that uniquely modulate the synaptic vesicle protein SV2A, which plays a central role in synaptic transmission (the communication between neurons in the brain). Find More Contacts for Syndesi Therapeutics, Edit Lists Featuring This Company Section, Novo Holdings Portfolio Company Syndesi Therapeutics acquired by AbbVie, Syndesi Therapeutics Announces Positive Results From Two Additional Phase I Studies Of Its Novel SV2A modulator SDI-118, Johnson & Johnson Innovation JJDC Portfolio Companies. The Walloon Region are creating a new and unique treatment approach using differentiated bone-forming cells round (. 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