Spark Therapeutics - Wikipedia Spark Therapeutics Spark Therapeutics, Inc. is a developer of gene therapy treatments, which treat debilitating genetic diseases. PHILADELPHIA, Oct. 22, 2013 /PRNewswire/ --Spark Therapeutics, a new, fully integrated company developing gene-based medicines for a wide range of debilitating diseases, announced today it has launched with a $50 million capital commitment from The Children's Hospital of Philadelphia (CHOP) to advance and commercialize multiple ongoing programs with clinical proof of concept. Head of Corporate Security. SaaS, Android, Cloud Computing, Medical Device). Spark Therapeutics has 368 employees, and the revenue per employee ratio is $254,076. The companies will work together on a worldwide basis with the aim of bringing an important investigational therapy to patients. Environmental, Social and Governance (ESG), HVAC (Heating, Ventilation and Air-Conditioning), Machine Tools, Metalworking and Metallurgy, Aboriginal, First Nations & Native American. What is Spark Therapeutics's Revenue? 81% of employees would recommend working at Spark Therapeutics to a friend and 70% have a positive outlook for the business. After extensive research and analysis, Zippia's data science team found the following key financial metrics. NGK 2625: 12 mm x 1.25 mm:. High, M.D, a gene therapy pioneer who has served as the director of the CCMT since its inception. Spark plans to leverageSPK-RPE65to address a broad spectrum of blinding conditions, and also has established a pipeline of gene therapy candidates to treat hematologic and neurodegenerative disorders. First participant dosed in the RESOLUTE SM trial, a Phase 1/2 dose-escalation study of SPK-3006. Hemophilia B is a serious and rare inherited hematologic disorder, characterized by a mutation in the Factor IX, or FIX, gene, which leads to deficient blood coagulation and an increased risk of bleeding or hemorrhaging. "We at CCMT have persevered through more than a decade of scientific and clinical development and are now closer than ever to realizing the ambitious vision of one-time, potentially curative therapies to address serious genetic conditions. Spark Therapeutics, Inc. focuses on the development of gene therapy products for patients suffering from debilitating genetic diseases. (Animal Production and Products) Association of Research Directors (ARD) 2013 . Part # 7034. Sparks expertise across research, clinical, regulatory and manufacturing builds on a legacy of innovation and excellence in gene therapy established by Sparks team while at The Childrens Hospital of Philadelphia Center for Cellular and Molecular Therapeutics. Spark Therapeutics Philadelphia, PA 19102 (PHILADELPHIA County) In-Person. This rating has been stable . Spark Therapeutics uses 27 technology products and services including HTML5, Google Analytics, and jQuery, according to G2 Stack. Spark Therapeutics is developing potentially curative, one-time gene therapy products to transform the lives of patients and re-imagine the treatment of debilitating diseases. Spark Therapeutics is actively using 64 technologies for its website, according to BuiltWith. Many of the CCMT's leaders will assume management roles within Spark or engage with the company as scientific advisors, including Katherine A. Spark Therapeutics is comprised of over 800 employees with its headquarters situated in Philadelphia, USA. When typing in this field, a list of search results will appear and be automatically updated as you type. Types of diversity represented in an organization, specifically of those who are founding members, currently the CEO, or have check-writing abilities in an investment firm. Spark Therapeutics does not accept unsolicited resumes/candidate . San Francisco Bay Area, Silicon Valley), Operating Status of Organization e.g. Spark will be responsible for conducting all Phase 1/2 studies while Pfizer will assume responsibility for pivotal studies, any regulatory approvals and potential global commercialization of the product. Spark's current valuation leaves room for substantial upside in the following years. from 8 AM - 9 PM ET. The founding team includes scientists who have led the advancement of gene therapy . Spark Therapeutics, Inc. is a developer of gene therapy treatments, which treat debilitating genetic diseases. This feature is in beta and may change with future updates. Spark's hemophilia B program has the potential to build on our leading hemophilia portfolio and could offer patients with this bleeding disorder a potential new treatment option.". Spark's initial focus is on treating orphan diseases where no, or only palliative therapies, exist. Limited products and pipeline Career advancement opportunities limited. Type Public Founded 2013 HQ Spark Therapeutics, Inc. 3737 Market Street Philadelphia, PA 19104 Phone: 1-855-SPARKTX / +1 215-220-9300 2022 Spark Therapeutics, Inc. P-RPE65-US-450002-10 Company Type For Profit. When typing in this field, a list of search results will appear and be automatically updated as you type. Its pipeline includes a product candidate targeting choroideremia (CHM), which is in a Phase I/II clinical . Spark Therapeutics, a fully integrated company, strives to challenge the inevitability of genetic disease by working to discover, develop and deliver gene therapies that address inherited retinal diseases (IRDs), neurodegenerative diseases, as well as diseases that can be addressed by targeting the liver. Its products include vor etigene neparvovec, which is in Phase III clinical trial for the treatment of genetic blinding conditions called inherited retinal diseases caused by non sex-linked, autosomal recessive . Dec 08, 2014, 07:30 ET. The Company focuses on treating orphan diseases. There are 69 replacement spark plugs for Champion CJ7Y. The open-label, randomized, controlled study builds on an earlier clinical study in which 12 patients with RPE65-related blindness demonstrated notable improvement in visual function, moving in some cases from being profoundly blind to being able to recognize faces and ambulate independently. Trademark applications show the products and services that Spark Therapeutics is developing and marketing. Sep 2015 - May 20171 year 9 months. View contacts for Spark Therapeutics to access new leads and connect with decision-makers. Find More Contacts for Spark Therapeutics, Diversity Spotlight (US Headquarters Only), Edit Lists Featuring This Company Section, Chroma Medicine Welcomes Spark Therapeutics Co-Founder and Former Founding CEO Jeff Marrazzo to Board of Directors, Power Moves: CEO Jeff Marrazzo is leaving Spark Therapeutics, 3 years after that giant acquisition, Spark Therapeutics Announces Departure of CEO and Founder Jeff Marrazzo; COO Ron Philip Named as Successor, Northeastern US Acquired Companies With More Than $1B in Revenue, Great Lakes Acquired Companies With More Than $10M in Revenue, Great Lakes Companies With More Than $1B in Revenue, Pennsylvania Acquired Companies With More Than $50M in Revenue. Spark Therapeutics is a publicly traded company on NMS using the ticker symbol ONCE. This program leverages a long track record of hemophilia B gene therapy research and clinical development conducted by Spark and its founding scientific team over the past two decades. The company's expertise across research, clinical, regulatory and manufacturing builds on a legacy of innovation and excellence in gene therapy established by Spark's team while at The Children's Hospital of Philadelphia Center for Cellular and Molecular Therapeutics. Associate Professor of Neurology. The company's product candidates are in the field of retina-directed gene therapies, liver-directed gene therapies, and central nervous . We are a force of over 90,000 people working together across more than 100 countries. It has a pipeline of product candidates targeting multiple rare blinding conditions, hematologic disorders and neurodegenerative diseases. Spark's most advanced clinical program is a Phase 3 study to address blindness caused by mutations in the RPE65 gene. All news about SPARK THERAPEUTICS INC. CombiGene's and Neurochase's preclinical study provides valuable information for the up.. GMP production of CG01 made available for preclinical studies planned to enable First i.. Get company contacts Spark Therapeutics Launched with $50 Million in Financing to Advance Late- and Mid-Stage Gene Therapy Programs with Clinical Proof of Concept . There is currently no pharmacologic treatment for this form of inherited retinal degeneration, which ultimately causes irreversible blindness. Developed and implemented strategic repositioning, restructuring, and full operational management . Notably, Spark has exclusive rights to commercialize CHOP's proprietary manufacturing technology and will use clinical . from 8 AM - 9 PM ET. Environmental, Social and Governance (ESG), HVAC (Heating, Ventilation and Air-Conditioning), Machine Tools, Metalworking and Metallurgy, Aboriginal, First Nations & Native American, www.sparktx.com/pipeline/hematologic-disorders, http://www.prnewswire.com/news-releases/spark-therapeutics-announces-gene-therapy-collaboration-in-hemophilia-b-with-pfizer-inc-300005849.html. Enrollment of approximately 20 total study participants is ongoing. Spark's initial focus is on treating orphan diseases where no, or only palliative therapies, exist. All school-age patients enrolled in the trial were able to transfer from Braille classrooms to sighted classrooms. Which investors participated in the most funding rounds? [1] It is a subsidiary of Hoffmann-La Roche . The average Spark Therapeutics salary ranges from approximately $93,180 per year for a Research Associate to $158,235 per year for a Senior Scientist.The average Spark Therapeutics hourly pay ranges from approximately $44 per hour for a Research Associate to $66 per hour for a Project Manager.Spark Therapeutics employees rate the overall compensation and benefits package 4.6/5 stars. Its products include LUXTURNA (voretigene neparvovec) for the treatment of patients with confirmed biallelic RPE65 mutation-associated retinal dystrophy and viable retinal cells. The founding team includes scientists who led the movement to develop gene therapy as a new treatment paradigm, establishing clinical proof of concept in the eye and liver and contributing key insights to the field that have resulted in a resurgence of industry interest in gene-based medicines. Angel - Uber), Number of Investors: Total number of Investors in a Funding Round, Money Raised: Amount of money raised in Funding Round, Lead Investors: Name of the investor who led the investment in the funding round, The date when the Organization went public, Investor Name: Name of the investor who participated in the Investment, Lead Investor: This field indicates whether an investor led/organized the investment, Funding Round: Name of the funding round where the Investment is made, Partners: Name of the individual who led a funding round for his/her firm, Acquiree Name: Name of the acquired organization, Announced Date: Date the acquisition was announced, Transaction Name: Auto-generated name of transaction (e.g. Spark's most advanced product candidate,SPK-RPE65, is in a fully-enrolled pivotal Phase 3 clinical trial for the treatment of a rare blinding condition. To learn more, visitwww.sparktx.com. We have built a fully integrated company, combining our proprietary adeno-associated viral (AAV) gene therapy platform with excellence in R&D, manufacturing and . To learn more visit www.sparktx.com. Spark is a gene therapy leader seeking to transform the lives of patients suffering from debilitating genetic diseases by developing one-time, life-altering treatments. Pfizer is a leader in hemophilia, developing the first recombinant Factor IX product," said Dr. Katherine High, a hematologist and co-founder, president and chief scientific officer of Spark. Media Inquiries: Jessica Rowlands 202-729-4089 [emailprotected], Cision Distribution 888-776-0942 About Spark Therapeutics. Spark has entered into agreements with multiple academic institutions to assemble the technology, programs and capabilities needed to deliver its pioneering gene therapy products. Spark Therapeutics has acquired Genable Technologies Ltd. on Mar 7, 2016. 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